ADC TOXICITY ATLAS
Atlas
Payloads and Linkers
Payloads
Targets
Query
Methods
← Targets
Target
Globo H (globo-H hexasaccharide; tumor-associated glycosphingolipid antigen, not a protein)
Gene
FUT1/FUT2
Other
ADCdb · TAR0RBHCF ↗
Target expression
Eye-tissue expression
Cornea · central
-
Cornea · limbal
-
Conjunctiva
-
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
1 agent
ADCs against this target
Any-grade
Grade 3+
Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
OBI-999
Monomethyl auristatin E (MMAE)
0
20
33.3
0
0%
severity
100%
0
Assessed · clear
true 0%
No data
never assessed