ADC TOXICITY ATLAS
Atlas
Payloads and Linkers
Payloads
Targets
Query
Methods
← Payloads & linkers
Linker · Cleavable dipeptide
maleimidocaproyl-valine-citrulline-PAB
Enzymatic
structure not applicable
Physicochemistry
Properties
MW
-
TPSA
-
xLogP
-
Formula
-
Cleavage
Enzymatic
Attachment
Maleimide
1 agent
ADCs built on this linker
Any-grade
Grade 3+
Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
JK-06
TPBG
10
5.9
10
5.9
8.8
0%
severity
100%
0
Assessed · clear
true 0%
No data
never assessed